Browsing University Library Papers and Theses by Subject "Azasugars"

Now showing items 1-3 of 3

The Synthesis of Azasugars Using an I2-mediated Carbamate Annulation

Win-Mason, Anna Louise (Victoria University of Wellington, 2012)

The biological activity of azasugars has largely been attributed to their ability to mimic the oxocarbenium ion-like transition state formed during reactions with carbohydrate-processing enzymes and, for this reason, ...
The Synthesis of Carbohydrates for the Treatment of Disease

Dangerfield, Emma Marie (Victoria University of Wellington, 2011)

In this thesis I investigated two aspects of glycobiology. In the first, I investigated the potential of α-GalCer analogues to be used in cancer immunotherapy. Two 4-deoxy α-GalCer analogues, with either a sphinganine or ...
Synthesis of N-Glycans and Azasugars to Target Disease

Moggré, Gert-Jan (Victoria University of Wellington, 2012)

In this thesis two aspects of carbohydrate research will be discussed. First, the total synthesis of N-glycans found on allergens that are known to stimulate an allergic immune response and second, the synthesis of iminosugars ...