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Browsing School of Biological Sciences · Te Kura Mātauranga Koiora by Title

Now showing items 48-67 of 587

Can a gut helminth parasite influence Th2 inflammatory responses in the skin?

Meijlink, Kimberley Jayne (Victoria University of Wellington, 2017)

Helminth parasites are one of the most common infectious agents of humans and cause significant health and economic burdens in the countries they are endemic in, making elimination an important goal. However, epidemiological ...
Can You Teach an Old Parrot New Tricks? Individual Variation in the Problem-Solving Abilities of Wild Kaka (Nestor Meridionalis)

Loepelt, Julia (Victoria University of Wellington, 2016)

Identifying factors that may influence cognitive variation in the wild is essential for furthering our understanding of how ecological and evolutionary mechanisms shape cognitive phenotypes. Yet, studies on cognitive ...
Carbon Flux in the Temperate Zooxanthellate Sea Anemone Anthopleura aureoradiata

Gibbons, Christopher Lynton (Victoria University of Wellington, 2008)

This study investigated the algal density and growth, photophysiology and contribution of algae to animal respiration requirements (CZAR), in the symbiosis between the sea anemone Anthopleura aureoradiata and its dinoflagellate ...
The Cellular and Physiological Basis of Host-Symbiont Specificity in a Model Cnidarian-Dinoflagellate Symbiosis

Gabay, Yasmin (Victoria University of Wellington, 2018)

The ability of corals to form novel partnerships with symbionts that may be better suited to new environmental conditions is an important factor when assessing the ability for corals to adapt to climate change. However, ...
Cellular effects of gliotoxin: Evaluation of a proteomic, isotope-based method to detect reactive cysteines

Sondhauss, Sven (Victoria University of Wellington, 2014)

Cysteinyl residues in proteins are important for many cellular processes and unregulated modification of the cysteine thiol group can have negative effects on cell vitality and viability. In this thesis, the potential for ...
The Cellular Effects of Nicotine and Tobacco Particulate Matter on Monoamine Transporters

Danielson, Kirsty Maree (Victoria University of Wellington, 2013)

Cigarette smoking causes nearly 6 million deaths worldwide every year (WHO, 2011). Current smoking cessation therapies available to the public are only marginally effective (Jorenby, 2006; Balfour et al., 2000), partly due ...
Cellular Inflammation in Models of Acute Gout

Martin, William John (Victoria University of Wellington, 2008)

Gout is a common form of inflammatory arthritis that is caused by the precipitation of monosodium urate crystals (MSU) in the joints. The acute form of gout is associated with sudden painful inflammatory episodes characterised ...
Cellular Targets and Tumour Suppressive Mechanisms of Peloruside A

Chan, Ariane (Victoria University of Wellington, 2012)

Peloruside A (PelA) is a novel secondary metabolite isolated from the New Zealand marine sponge Mycale hentscheli. It is a potent microtubule-stabilizer and binds to a distinct site on β-tubulin compared to the widely ...
Characterisation and optimisation of nitroreductase-prodrug combinations for bacterial-directed enzyme-prodrug therapy

Chan-Hyams, Jasmine (Victoria University of Wellington, 2020)

Gene-directed enzyme-prodrug therapy (GDEPT) employs tumour-tropic vectors including viruses (VDEPT) and bacteria (BDEPT) to deliver a genetically-encoded prodrug-converting enzyme to the tumour environment, thereby ...
Characterisation of a dual-colour retinoic acid reporter system for analysing cells and embryos

Black, Bianca (Victoria University of Wellington, 2018)

Vitamin A is an important component in the diet as its metabolites, the retinoids, play key roles in a vast range of cellular functions, from production of germ cells, to embryonic development and right through until ...
Characterisation of a Novel Benzopyran Library Using High-Throughput Microscopy

Sheridan, Jeffrey Patrick Christopher (Victoria University of Wellington, 2017)

Drug discovery is a multi-disciplinary field incorporating both chemistry and biology to create novel pharmaceuticals. Nature synthesizes a diverse range of chemical entities that can demonstrate a wide range of biological ...
Characterisation of a Novel Nitrogen-Fixing, Polyhydroxyalkanoate-Producing Bacterium, Novosphingobium Nitrogenifigens Y88T

Smit, Anne-Marie (Victoria University of Wellington, 2008)

The novel sphingomonad Novosphingobium nitrogenifigens Y88T (Y88T) is an obligate aerobe able to grow in nutrient-imbalanced environments where nitrogen is naturally limiting, but carbon is found in abundance. Due to its ...
Characterisation of the Genes Encoding Mannuronan-C5-Epimerase in the Brown Alga Lessonia Variegata

Ghosh, Sayani (Victoria University of Wellington, 2012)

Alginate is known to be a commercially valuable polysaccharide, of great importance in industries such as food, cosmetics, medicine and pharmaceuticals. It is obtained commercially by harvesting brown algae. The final ...
Characterisation of the immune cells and cytokines involved in a model of atopic dermatitis

Naidoo, Karmella (Victoria University of Wellington, 2018)

Atopic dermatitis (AD) is a highly debilitating disease with significant health impacts worldwide. It is a chronic and relapsing inflammatory skin disease which often poses a life-long burden for the affected individuals. ...
Characterisation of the Mitochondrial Genome and the Phylogeographic Structure of Blue Cod (Parapercis colias)

Smith, Hayden Murray (Victoria University of Wellington, 2012)

This thesis primarily addresses the genetic population structure of blue cod (Parapercis colias) in the New Zealand Exclusive Economic Zone, within which approximately 2800 Tonnes of the endemic fish are harvested annually. ...
Characterising the benthic Phormidium autumnale-dominated biofilm community and anatoxin production throughout biofilm succession

Brasell, Katie Anne (Victoria University of Wellington, 2014)

There has been an increase in the prevalence and intensity of Phormidium autumnale-dominated benthic blooms in New Zealand over the last decade. This species produces the potent neurotoxins Anatoxin-a, Homoanatoxin-a and ...
Characterization of Symbiodinium-associated viruses and implications for coral health

Lawrence, Scott Anthony (Victoria University of Wellington, 2014)

Coral reefs are in decline worldwide. Much of this decline is attributable to mass coral bleaching events and disease outbreaks, both of which are linked to anthropogenic climate change. Despite increased research effort, ...
The Characterization of TA-289, a Novel Antifungal from Fusarium sp.

Quek, Natelle C H (Victoria University of Wellington, 2011)

Natural products offer vast structural and chemical diversity highly sought after in drug discovery research. Saccharomyces cerevisiae makes an ideal model eukaryotic organism for drug mode-of-action studies owing to ease ...
Characterization of the Coral Disease 'Porites Bleaching with Tissue Loss' (PBTL) From Hawaii

Sudek, Mareike (Victoria University of Wellington, 2013)

Coral reefs around the world are facing many threats and have sustained severe losses in coral cover over the past few decades. Coral bleaching and disease outbreaks have contributed substantially to this reef decline, ...
Chemical genetic analyses of compounds derived from feijoa fruit

Mokhtari, Mona (Victoria University of Wellington, 2017)

Nature has been a rich source of pharmaceutical compounds, producing 80% of our currently prescribed drugs. The feijoa plant, Acca sellowiana, is classified in the family Myrtaceae, native to South America, and currently ...