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Browsing School of Biological Sciences · Te Kura Mātauranga Koiora by Title

Now showing items 245-264 of 587

Identification, Documentation and Control of Biological Contamination in Middle Distillate Fuel

Hettige, Gloriah Emly Gres (Victoria University of Wellington, 1987)

The present study was initiated under a contract with the New Zealand Defence Scientific Establishment to document the nature, extent and possible sources of microbial contamination of middle distillate fuel ('Dieso' ) ...
Identification of a meningococcal adhesin that inhibits epithelial cell migration

Greig, Gabrielle (Victoria University of Wellington, 2020)

Neisseria meningitidis virulence is polygenic, therefore comparing many genomes may not yield strictly disease-associated virulence factors. An alternative approach is comparing closely related isolates, such as those from ...
Identification of Anti-tubercular Compounds in Marine Organisms from Aotearoa

Dasyam, Nathaniel (Victoria University of Wellington, 2014)

Tuberculosis (TB) is responsible for more than one million human deaths per year globally, more than any other disease caused by a bacterial pathogen. Although effective treatments exist, the long duration of the current ...
Identifying Human Host Cell Protein Targets of the Bartonella Effector Protein (Bep) Fic Domains

Trounson, Vaughan (Victoria University of Wellington, 2016)

The genus Bartonellae represents an increasing number of emerging bacterial pathogens that utilises an unusual infection strategy, parasitising the red blood cells of their mammalian host. The most common species to infect ...
Identifying mechanisms of population change in two threatened grizzly bear populations

McLellan, Michelle (Victoria University of Wellington, 2020)

Identifying the mechanisms causing population change is essential for conserving small and declining populations. Substantial range contraction of many carnivore species has resulted in fragmented global populations with ...
Identifying the Mechanism of Action of Bioactive 1,2-Cyclopropyl Carbohydrates

Lassueur, Loïc (Victoria University of Wellington, 2015)

Cyclopropanes and carbohydrates have long been used in the field of drug development. Previous work has shown that 1,2-cyclopropyl carbohydrates display bioactivity in both HeLa cancer cell lines¹ and in yeast² with a ...
Immune Responses in Perforin Deficient Mice

Simkins, Helen Mary Alys (Victoria University of Wellington, 2009)

Dendritic cells (DC) play a pivotal role in the initiation of T cell responses and earlier studies have shown that their survival is important for the generation of effective immune responses. Cytotoxic T lymphocytes (CTL) ...
Impact of Environmental Stressors on the Metabolic Functioning of a Temperate Cnidarian-Dinoflagellate Symbiosis

Bone, Oliver (Victoria University of Wellington, 2016)

Cnidarian-dinoflagellate symbioses occur across a wide latitudinal range, from temperate to tropical locations in both hemispheres. In the tropics, this association provides the foundation for the development of highly ...
Impact of the local environmental variability on the patterns of coral recruitment on Indo-Pacific reefs

Boschetti, Simona Tiziana (Victoria University of Wellington, 2016)

Coral reefs are threatened by a range of human activities at both local and global scales. The result of these impacts has resulted in a worldwide decline in the coral reef ecosystems. Corals are the principle reef builders ...
The impact of thermal stress and nutrient availability on the physiology and proteome of symbiotic dinoflagellates

Newson, Grace (Victoria University of Wellington, 2019)

Scleractinian corals, which form the building blocks of tropical reefs, are reliant on a mutualistic symbiosis with phototrophic dinoflagellates of the family Symbiodiniaceae for their metabolic needs and survival. ...
The impacts of an introduced mammalian predator (Mus musculus) on tree weta (Hemideina trewicki) and skinks (Oligosoma polychroma, Oligosoma infrapunctatum and Oligosoma lineoocellatum) in Cape Sanctuary, Hawkes Bay

Dent, Emma (Victoria University of Wellington, 2016)

The introduction of exotic species, particularly predators, into new ecosystems is one of the biggest causes of loss of biodiversity across the globe. Understanding the impacts that introduced species have on native species ...
Impacts of Environmental Changes on the Use of Cellular Storage Products in a Temperate Cnidarian-Dinoflagellate Symbiosis

Fracasso, Lauren (Victoria University of Wellington, 2020)

Members of the phylum Cnidaria, such as corals and sea anemones, often form mutualistic endosymbiotic relationships with photosynthetic dinoflagellates that are founded upon a reciprocal exchange of nutrients. In this ...
Impacts of man-made structures on marine biodiversity and species status - native & non-native species

Pawaskar, Sonali (Victoria University of Wellington, 2020)

Coastal environments are exposed to anthropogenic activities such as frequent marine traffic and restructuring, i.e., addition, removal or replacing with man-made structures. Although maritime shipping and coastal ...
The impacts of ocean acidification and warming on the Antarctic bivalve, Laternula elliptica

Bylenga, Christine Heather (Victoria University of Wellington, 2016)

Laternula elliptica are large bivalves found in high densities in soft sediments in coastal regions of the Southern Ocean. L. elliptica form an important part of the ecosystem, due to significant sediment stabilisation and ...
The Impacts of Predation and Habitat Degradation on Coral Reef Sponge Assemblages in SE Sulawesi, Indonesia

Powell, Abigail (Victoria University of Wellington, 2013)

Coral reefs across the globe are in decline due to multiple threats including overexploitation, pollution, coastal development, climate change and ocean acidification. Much research has focused on the effects of these ...
The importance and movement of mud bacterial carbon within the symbiosis of the New Zealand sea anemone Anthopleura aureoradiata

Cornwall, Andrew (Victoria University of Wellington, 2017)

A. aureoradiata is New Zealand’s only native cnidarian to form a phototrophic symbiosis with dinoflagellate microalgae. It is of particular interest as it can be found in estuarine mudflat habitats attached to cockles, ...
Improving immunotherapy for high grade glioma

Hunn, Martin Kent (Victoria University of Wellington, 2015)

Glioblastoma multiforme (GBM) is a malignant primary brain tumour that is almost always fatal. Conventional treatment modalities are limited by toxicity. T cell-based immunotherapy is a promising alternative that has the ...
Induction of Anti-Tumour Immune Responses by Dendritic Cells Generated with Flt3-Ligand

Lim, So Nai (Victoria University of Wellington, 2011)

Dendritic cells (DCs) are potent antigen presenting cells that are crucial for the initiation of an immune response. Due to this property, DCs have been used as the basis of cancer vaccines in immunotherapy. In clinical ...
Inferring the late Quaternary phylogeography of Pseudopanax crassifolius using microsatellite analysis

Gemmell, Michael (Victoria University of Wellington, 2013)

Geologic processes have shaped the New Zealand archipelago throughout its existence. The last major geologic event was the Pleistocene glaciations beginning around 2.5 million years ago. This cold period left its mark in ...
The Influence of BCL6 on the WNT Pathway in Glioblastoma Therapy Resistance

Gordon-Schneider, Rosemary (Victoria University of Wellington, 2018)

Glioblastoma is a devastating disease with a median survival of 18 months from diagnosis and a 5 years survival rate of only 10%. The gold standard of treatment for glioblastoma is surgical resection followed by chemotherapeutic ...